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CBD

CBD Stands for Cannabinoid


My understanding is the best CBD supplies can be had though following this link.

https://www.cbdbiocare.com/deals/Buzcallchief/

April 21st 2019

“It’s made from one of the main compounds in marijuana,” the barista explained as I was taking my first sip of a hot chocolate at The End, an eclectic Brooklyn cafe known for creating the unicorn latte. I froze. Panic washed over me. It was 2017 and the last time I'd consumed any type of marijuana—more than three years before—I'd experienced paranoia, heart palpitations, and I'd fainted. (Yes, fainted. And yes, it was embarrassing.) The barista assured me that I would not get high from the CBD in my drink, so I kept sipping. Instead of panic, I felt a cozy sense of calm.

As someone who’s long suffered from anxiety (starting with general pangs of uneasiness about why we’re here on earth that date back all the way to Kindergarten, maybe even earlier), I wasn’t about to let my experience with CBD begin and end with that latte. Over the years I’ve learned to master my anxiety...er, at least I’ve befriended it so we can co-exist. I’ve done this mainly by accepting that this is just the way my brain works sometimes and limiting my intake of caffeine, alcohol, and sugar, and exercising and meditating regularly (if you have anxiety and haven’t tried these things—do). But despite all my progress, feeling anxious—even if it’s just occasionally—sucks. I don’t think anyone with anxiety would turn their nose up at a natural, quick fix.

On the G train home, I took out my phone and started Googling CBD—short for cannabidiol, one of the many compounds found in the marijuana plant. I was fascinated by the idea that I might benefit from a plant I had long regarded as “not for me.” My search led to a lot of confusing and convoluted articles, most of which were written by people peddling CBD products. I have two science degrees and still found myself confused about how CBD, hemp, marijuana, THC, and cannabis all fit together. The confusion made me all the more motivated to figure out exactly how to use CBD the correct way.

As someone who’s been studying alternative medicine and herbs for years, I knew that cannabis was one of the most powerful plant medicines ever discovered. To be honest I’d always been bummed that seemingly something about my physiology meant I would never really understand its benefits. But here was a realization. I was hooked on the idea that I'd just been underestimating the complexity of the plant and that there was hope yet for cannabis and me.

I started experimenting with different doses and delivery methods, looking for the moment when I understood what all the fuss was about. I’d felt calm after that first latte, but one experience wasn’t enough to convince me it was anything more than a hope-filled placebo effect. I wanted to crack the code on CBD and figure out an exact equation, something like: I took X amount of CBD via Y delivery method and got Z effect. The second time I tried CBD is was a sublingual oil at 5 milligrams (mg), which seemed to do nothing. Then I tried 40 mg twice a day and felt sleepy and lightheaded. I moved on to creams, balms, tinctures, sprays, vape pens, bath bombs, drinks, eye creams, and serums. There’s no official dosage recommendations for CBD; this sloppy trial-and-error approach is pretty standard for the newly curious.

.By the end of that year of experimentation, I was so deep down the cannabis rabbit hole that I’d begun writing what ultimately turned into my first book, CBD Oil: Everyday Secrets. I was also working full-time at a media company, meaning the book was written in what felt like 80, 35-minute increments that were squeezed in at 11 p.m. on Tuesdays, 8 a.m. every other Monday, and on the weekends when all my friends were being carefree and eating tacos without me—which triggered some major anxiety. Much to my dismay, it turns out that writing a book about a compound with anti-anxiety benefits does not make you immune to book-related anxiety. (Even in my most panic-ridden moments, the irony of having CBD book–fueled anxiety was not lost on me). But I just doubled down on the idea that clearly, we could all benefit from some all-natural anxiety relief.

My research took an important turn when I leaned that the best CBD products offer an “entourage effect:” when THC and other compounds in the cannabis plant help bolster CBD’s unique anti-inflammatoryimmunomodulating, and anxiolytic properties. This entourage effect seemed like some abstract trip until I experienced it first hand. While visiting California in early 2018, I kept seeing non-psychoactive, high-CBD cannabis oils sold in dispensaries across the state. More accurately, most of the high-CBD cannabis oils were sold outdue to the high demand. I tried out some of these California CBD oils, which are differentiated mostly by the ratio of CBD:THC they contain, looking for the ultimate ratio for my anxiety. I (very cautiously) made my way from 30:1 to 20:1, 18:1 to 10:1, and all the way down to 8:1, which is considered the threshold for intoxication. Of course there were a few mishaps, since not all brands test their products' THC content and others often mislabel their offerings. But I slept them off, ate some snacks, and learned to distinguish the good brands from the not-so-good ones.

.

One of my favorites? Care By Design. I visited their manufacturing facility in Northern California, had a two-hour-long conversation with their chief scientific officer, and settled on their 18:1 CBD:THC oil. I take two or three drops under my tongue and the results are subtle but nice. When I’m in the crowded train carrying three heavy bags, I don’t feel cortisol coursing through my veins in quite the same way. When I’m bombarded with emails and a million tasks to complete in one day, I’m better able to sit still and tick them off one by one without my body going haywire.

I also keep the 8:1 CBD:THC ratio oil from Care by Design on hand, mainly for flights and acute anxiety situations like a panic attacks. The effects of the 8:1 are noticeable—I might equate it to a very subtle xanax.

If I’m using one of the hemp-based CBD oils available in all states, I take a 15 to 20 mg dosage of CBD oil by Lord Jones or Bloom Farm when I’m stressed, traveling, or feeling less-than-optimal. (It’s a life-saver if I’ve had one too many cocktails the night before.) I also use a combined CBD and THC topical balm from Papa & Barkley on my chronic neck and jaw pain, which is exasperated by my anxiety and the fact that, like so many people in 2019, I sit staring at a screen for most of the day. I've tried everything for my neck pain—from acupuncture and chiropractic work to physical therapy and massage. These all helped to varying degrees but nothing gave me quick relief except Advil, which has been problematic since I’ve basically made it my life’s mission to reduce my use of over-the-counter and prescription drugs.

.

When I discovered topical cannabis lotions (I use one that’s even higher in THC—a 1:3 ratio of CBD:THC—since applying it topically won’t give you a negative reaction), it changed the game for me. Even though cannabis is expensive, it’s nothing compared to going to physical therapy twice a week. The science on topical applications of CBD is still very much in development, but I can tell you that it really, really works for me.

I started using CBD as a total skeptic. But after I did my research, it upended my life: my approach to stress management, how I feel about cannabis as a whole, even my career. Many people still feel the way about CBD that I used to. But my hunch? Pretty soon our entire country's opinion of CBD will be changed, too.

 

Sept 29th 2018

Mum who took illegal cannibis oil given all clear

Fifty two-year-old Joy Smith was diagnosed with incurable stomach and bowel cancer in August 2016.

But in an attempt to defy expectations, she started taking cannabis oil that contained THC, which is illegal in the UK.
According to the Daily Mail, following a rollercoaster two years, Joy found out on Monday morning that she was cancer-free and would no longer require chemotherapy.

Joy, from Coventry, West Mids, said: “I am going to party for the rest of my life. I have got to be the only person in the world to have survived this.

“I keep pinching myself to see if this is real. I am being monitored every three months, but other than that I have no more treatment planned.”

Back in 2016, Joy was told she would have around six weeks left to live and chemotherapy would merely buy her more time.
So she started having treatment every two weeks for three days, but had to have the line that delivered her chemotherapy taken out after she developed sepsis.

In the background, Joy’s pals had been researching alternative ‘cures’ until she was handed a cannabis-based tablet.

She admitted that she didn’t want to take it as first because she ‘didn’t know what it was’ but did so anyway, with all other hopes of a cure receding.

She claims that the THC left her feeling ‘drunk’ and she struggled to speak with words coming out ‘slurred’.
However, after taking regular doses of the cannabis oil, her once inoperable tumours almost completely disappeared.

The mum spoke about her battle against the cancer with the oil in March, when scans showed just a small amount of the disease left in her stomach.

With hope restored, she continued her treatment and she hasn’t stopped smiling since the appointment with her consultant on Monday. She said the news has yet to sink in.

She said: “I am just so happy. This is all down to the cannabis oil. I shouldn’t be here, but I am.
“My daughter is in Australia at the minute and when I told her she thought I was lying.

“Everyone around me has been amazing, I have an army behind me and they’re all so happy.”

Now Joy is writing a book about her journey so far and is determined to get THC legalised.

She said: “I have got to get it legalised. I am so happy, happier than I have ever been. I just keep sharing the petition and hope it will make a difference.

“I believe my reason for being here is to help everyone else. Unless you have been faced with death you don’t know.”

She has started a petition to make cannabis oil legal in the UK for medicinal use, which has attracted more than 17,000 signatures.

 

Sept 2nd 2018

Cannabis extract can help treat psychosis, study suggests

'Our results have started unravelling the brain mechanisms of a new drug that works in a completely different way to traditional anti-psychotics'

cannabis extract could help treat symptoms of psychosis even though the mental health condition has been linked to long-term recreational use of the drug, UK researchers have found.

The team from King’s College London found cannabidiol (CBD), one of the major chemical components of the marijuana plant, works in opposition to its other ingredient, THC (tetrahydrocannabinol), which causes users to get “high”.

THC is thought to be a significant risk factor for psychosis and other conditions like schizophrenia.

Experts have warned modern “skunk” strains that have been bred to maximise levels and produce a stronger high can harm users. People with psychosis experience episodes of acute hallucinations that can become distressing and put them and others at risk. 

The King's study found that a single dose of CBD could significantly reduce the abnormal brain activity that causes these effects.

“There is an urgent need for a safe treatment for young people at risk of psychosis,” said Dr Sagnik Bhattacharyya, from the Institute of Psychiatry, Psychology & Neuroscience at the university. “The mainstay of current treatment for people with psychosis are drugs that were first discovered in the 1950s and unfortunately do not work for everyone.

“One of the main advantages of cannabidiol is that it is safe and seems to be very well tolerated, making it in some ways an ideal treatment.”

CBD is not psychoactive and does not have opportunities for abuse, with legally sold forms having to be extremely low in THC.

A CBD oil with higher THC has been licensed for treating rare childhood epilepsy in the US. This, along with growing evidence for its health effects, has led the UK government to recognise the benefits of medical cannabis and say it could be prescribed bydoctors.

To test how CBD may counteract these effects the researchers recruited 33 young people flagged by early intervention services as having symptoms of psychos, but who had yet to be diagnosed or treated.

Alongside 19 healthy participants their brain activity was scanned and their verbal and memory skills were tested before half were given CBD and the other half received a placebo.

The findings, published in the Journal of the American Medical Association: Psychiatry, showed that brain activity was abnormal for all the patients with psychosis prior to treatment.

However, after treatment those who received CBD shoed greatly reduced abnormal activity, falling between the placebo and healthy group, and their test performance improved.

While these findings are promising they are now launching the first major clinical trial, across multiple hospital sites, to confirm whether CBD can be an alternative for conventional antipsychotic drugs.

“If successful, this trial will provide definitive proof of cannabidiol’s role as an antipsychotic treatment and pave the way for use in the clinic,” Dr Bhattacharyya said. “Our results have started unravelling the brain mechanisms of a new drug that works in a completely different way to traditional anti-psychotics.”


May 14th 2018

CBD Oil for Diabetes: All You Need to Know

Diabetes is a disease wherein the body has trouble regulating the level of sugar (glucose) in the bloodstream. In healthy individuals, the pancreas produces a hormone called insulin, which works to transport glucose molecules across cell membranes and into cells for energy production.

In diabetics, depending on whether they suffer from the Type 1 or Type 2 form of the disease, the body is either unable to produce insulin, or it’s unable to use it in a way that’s sufficient enough to maintain glucose at a healthy level in the bloodstream.

In turn, irregular or unstable glucose levels can cause a huge array of serious, life threatening conditions, which we’ll talk about in detail shortly.

In regard to CBD oil for diabetes, then, there are two main things we need to consider in order to determine the degree of viability that the drug has on the increasingly-prevalent disease: In what ways (if any) does CBD work to improve either the function and/or production of insulin, and how does CBD work to alleviate the spectrum of side effects caused by irregular blood sugar levels.

In this article, we’ll talk about recent research publications which directly address both of these questions, in the hopes of shedding some light on why CBD oil for diabetes is gaining such popularity among both patients and physicians alike.

Diabetes: What is it, What Causes it, and Who is at Risk
To elaborate on the rudimentary processes explained in the introduction, diabetes is a disease wherein the body is unable to properly transfer the glucose from food into energy sources for cells.

And of course, without energy sources, the body’s cells (which are responsible for every functional mechanism of life) will be unable to carry out the requisite pathways needed to survive.

In the case of Type 1 diabetics (who only make up about 5% of the diabetic population), the body is no longer able to produce insulin, which is the keystone hormone needed to transfer glucose molecules from the bloodstream into cells. This is generally due to an autoimmune attack on the pancreas – the organ responsible for the production of insulin. Type 1 diabetes usually arises in children or young adults who contract a pancreas-attacking virus, and other than perhaps a genetic predisposition, there are not many specific risk factors.

Type 2 diabetes is a rather more complex form of the disease wherein the body still produces insulin, but it either doesn’t produce enough of it, or the cells become resistant to its physiological pathways. Either way, the resulting effect is similar to that of Type 1 diabetes, wherein the underlying issue is a general inability to control blood glucose levels.

Also, Type 2 diabetes is a far more prevalent form of the disease; it is estimated to affect over 400 million people worldwide, or between 90 and 95% of the total diabetic population.

Additionally, far more risk factors are associated with Type 2 diabetes than there are with Type 1. Several of the most prominent of these factors include: weight (obesity); a high sugar diet combined with inactivity; family history/genetics; ethnicity (African-Americans, Hispanics, and American Indians are especially susceptible, though the reason is unknown); and age (people over 45 are far more likely to develop the disease).

Like we mentioned earlier, in the world of medicine, anecdotal evidence can only go so far.

So regardless of the fact that many diabetics use CBD oil every day of their lives to help manage their condition, a lot of physicians will be wary to recommend it as a treatment unless they can point to the exact physiological reasons as to why it’s beneficial.

Fortunately, along with its treatment potential for cancer and nervous disorders, CBD oil for diabetes has been one of the most thoroughly researched areas of medicinal cannabis.

Dr. Raphael Mechoulam, a research scientist out of the Hebrew University of Jerusalem, points to the fact that naturally-occurring CBD receptors occur throughout the human body – from the brain and nervous tissues, to organs and immune cells, and one of the organs where he’s found the receptors to be highly prevalent.

The pancreas.

In fact, endocannabinoid receptors (namely CB-1 receptors) have been found specifically in the organ’s islet cells – the exact location where insulin is produced. And what’s more, the stimulus of these receptors in the islet cells has already shown to have direct links to insulin production.

Now, regardless of how intriguing the research is, we simply cannot yet say that endocannabinoid receptors are directly responsible for the production of insulin, or that CBD is a cure for diabetes in any way shape or form. While it’s possible that the receptors may play a crucial role in insulin’s production, much more research will have to be done in order to pinpoint the physiological mechanisms and exact chemical pathways that are responsible for doing so.

We will say, though, that preliminary studies of CBD for diabetes have been so promising, it’s led to American Journal of Medicine’s Dr. Joseph Alpert to call on the DEA and the National Institute of Health (NIH) for increased funding and collaboration on it’s continued research.

And moreover, the National Organization for the Reform of Marijuana Laws (NORML) has gone so far as to suggest that endocannabinoids may be “the most important physiologic system involved in establishing and maintaining human health,” based on their central role in regulating homeostasis, which is the body’s ability to maintain normative operating conditions in spite of harmful stimuli.

CBD for Diabetes: How it Can Help Treat Underlying Medical Conditions.

What’s been even more concrete than research on CBD’s role in insulin production, though, has been research on its ability to help treat and prevent common medical conditions associated with diabetes.

One of the most prominent factors associated with the development of insulin resistance in Type 2 diabetes is chronic inflammation related to obesity. The excessive presence of fatty tissue in obese Type 2 diabetics drastically limits the efficiency of glucose metabolism, which in turn results in high levels of sugar building up in the bloodstream. The specific anti-inflammatory properties of CBD, however, have long been known to directly combat glucose metabolic disorders and improve overall metabolism.

Nerve damage is another condition commonly associated with diabetes. In many instances diabetics will have very limited sensation in their lower extremities, and in severe cases, amputations of the leg(s) are often necessary. This is due to a lack of sufficient blood flow, which eventually results in the breakdown of tissue and the increased risk for infection. CBD, in turn, is a federally patented neuroprotectant, and has been shown to reduce infarcts (areas of dead tissue due to lack of blood flow) by up to 30%.

Likewise, there have been dozens of other publications as well that have showed great promise in the role of CBD as a treatment for diabetes, including studies on retinopathy (a disorder of the eyes) and diabetic cardiovascular dysfunction.

In short, the medical potential and therapeutic benefits of CBD oil for diabetes is nothing short of phenomenal; many thousands of diabetics use it every day to treat the disease and improve their overall quality of life, and many thousands more will continue to do so in the future in light of increased research and improved information.

And lastly, on a side note, it’s important to point out that CBD oil will not get you high – unlike whole plant marijuana, it contains hardly any traces of THC, which is the specific cannabinoid responsible for the psychoactive properties of the drug.

CBD Oils for Diabetes: Final Thoughts.

CBD oils can range in terms of their overall concentrations of the active cannabinoid; not all tinctures are the same, and different dosages will be required depending on the specific oil that you end up using (although the dosage strength will always be labeled on the bottle).

CBD oil is no guaranteed solution for all diabetics; while the majority of patients do find it highly therapeutic, it’s certainly more effective for some than it is for others. As is always the case, it’s important to do your own research, and if possible, speak with a professional about some possible tinctures that might be appropriate for you and your specific condition.

You might want to investigate CBD oil from CTFO. This is a top quality hemp oil, grown in the US with certified lab testing and quality control for all products. It is available in a wide variety of strengths and flavoring (peppermint) is also available.

 

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