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Scientists halt diabetes with insulin cells

Dec 19th 2017

Social participation in clubs and groups has been linked to a lower risk of diabetes.

A study found that socially isolated individuals were diagnosed with Type 2 diabetes more often than individuals with larger social networks.

A lack of participation in clubs or other social groups was associated with 60% higher odds of pre-diabetes and 112% higher odds of type 2 diabetes in women compared to those with normal glucose metabolism.

In men, lack of social participation was associated with 42% higher odds of type 2 diabetes, the research carried out in the Netherlands found.

Men living alone was also associated with 94% higher odds of Type 2 diabetes.

Dr Miranda Schram, of Maastricht University, said: “High-risk groups for Type 2 diabetes should broaden their network and should be encouraged to make new friends, as well as become members of a club, such as a volunteer organisation, sports club or discussion group.

“As men living alone seem to be at a higher risk for the development of Type 2 diabetes, they should become recognised as a high-risk group in health care. In addition, social network size and participation in social activities may eventually be used as indicators of diabetes risk.”

Lead author Stephanie Brinkhues said: “We are the first to determine the association of a broad range of social network characteristics – such as social support, network size or type of relationships – with different stages of type 2 diabetes.

“Our findings support the idea that resolving social isolation may help prevent the development of Type 2 diabetes.”

But they pointed out that the study does not allow for cause and effect, as early changes in glucose metabolism may cause people to feel tired and unwell, which could explain why individuals limit their social participation.

Nov 25th 2017

Using mouthwash twice a day increasing a person's chances of contracting diabetes by 50 per cent, a new study has claimed.

Scientists in the US claim those using over-the-counter mouthwash twice a day run a significantly higher risk of developing type 2 diabetes.

The author of the study, Professor Kamudi Joshipura, says mouthwash kills helpful as well as harmful bacteria, destroying those that protect against diabetes and obesity.

Prof Joshipura, a professor of epidemiology at the Harvard School of Public Health, found the risks were heightened for all mouthwash users, regardless of sex, weight or diet.

He said: "Most of these antibacterial ingredients in mouthwash are not selective.

"In other words, they do not target specific oral bacteria. Instead, these ingredients can act on a broad range of bacteria [including the protective ones]."

Another study, published earlier this year, found that some mouth bacteria help protect against both diabetes and obesity.

Leading diabetes experts in the UK have so far said it is too early to comment on whether dropping mouthwash could help protect against the condition.

Nov 23rd 2017

Diabetes is “decimating men”, with one in 10 now affected, a report by a men’s health charity has warned.

The report, created by the Men’s Health Forum, highlights that men are 26% more likely to develop type 2 diabetes than women, which can potentially have life-changing or even life-ending consequences.

The researchers also found that men are more likely to be overweight than women (with a body mass index of 25+), which is known to raise the risk of type 2 diabetes. However, men are also more likely to develop diabetes at a lower BMI than women.

Despite this, men are less likely to be aware that they are overweight or to participate in weight management programmes.

In light of the findings, the charity has called on the National Diabetes Prevention Programme to be better designed and delivered in ways that work for men.

Looking at NHS data, the research uncovered that the vast majority (69.6%) of diabetes patients presenting with a foot ulcer are men.

Furthermore, men were found to more be likely impacted by diabetic retinopathy -

which can affect eyesight - than women.

Worryingly, the stats indicated men are also more than twice as likely to have a major amputation as a result of diabetes than women.

Finally, the charity warned that men are more likely to suffer premature death as a result of diabetes than women.

The age-standardised mortality rate for men with an underlying cause of death as diabetes mellitus was found to be 40% higher than it is for women.

In light of the findings, the charity has called on health policy makers and practitioners to better engage men through:

NHS Health Checks

Routine eye tests

Weight management programmes

Diabetes education programmes

Martin Tod, chief executive of the Men’s Health Forum commented: “Men are more likely to get diabetes. More likely to suffer complications. More likely to face amputation as a result of diabetes. And more likely to die from diabetes.

“Diabetes is hitting men especially hard, but too little is being done to understand the problem and tackle the problem. The Men’s Health Forum wants to see a serious programme of research and investment to ensure men get the support and care they need to prevent and manage diabetes.

“The toxic combination of ever more men being overweight, men getting diabetes at a lower BMI and health services that don’t work well enough for working age men is leading to a crisis. We need urgent action.”

Peter Baker, Men’s Health Forum associate and the report author, added: “Diabetes has been described as a national health emergency but the burden of the disease on men has not been fully recognised or responded to by health policymakers and practitioners.

“What’s now urgently needed is an approach that takes full account of sex and gender differences so that both men and women’s outcomes can be improved.”

In response to the report, Professor Jonathan Valabhji, NHS England’s national clinical director for obesity and diabetes, told The Telegraph: “Men are at a higher risk of developing type 2 diabetes with a lack of exercise, poor diet and being overweight all risk factors to developing type 2 over time.

“Across the majority of England people at high risk can now get help on the NHS’s diabetes prevention programme, which is seeing almost as many men attend as women - a much higher proportion than usually seen in weight loss programmes.”

April 5th 2017

Sugar gets a bad reputation. And for a good reason. There are multiple unusual side effects of sugar. Added sugar can have multiple effects on the body, including its contribution to teeth decay, weight gain, heart disease, and yes, even cancer. But there is another side effect of sugar that nobody is talking about.

Natural vs. Artificial Sugar

The main difference between natural sugar and high fructose corn syrup is the balance of fructose and glucose in high-fructose corn syrup.

As the name suggests, there is more fructose in the syrup than in regular sugar. The difference, however, is that an apple contains fiber and other nutritious elements that outweigh its sugar content.

So how does an excess of sugar make one gain weight?

How It Works

When you ingest sugar, the liver metabolizes the fructose and converts it into fat. The spike in triglycerides also leads to a reduced amount of HDL cholesterol (or the 'good' kind of cholesterol).

What Too Much Sugar Can Do to You

Ingesting too much sugar hurts the metabolism and, over time, it weakens it. This causes metabolic dysfunction, meaning your insulin stops working properly. This is one major side effect that most people are unaware of.

This side effect can directly lead to obesity, heart disease, and type II diabetes. In addition, added sugar is especially addictive. So the more sugar you eat, the more likely you'll become addicted and reliant on it.

The best way to cut back on your sugar intake is to be aware of what and how much you eat. A sugary treat every once in a while is normal. Overindulgence in anything is where it gets dangerous. So, overall eat those foods with high sugar in moderation and remember healthy eating may be easier than you think.

June 8th

Did you know that you should not use Bazuka wart remover if you are diabetic, read the small print on the leaflet.

Scientists halt diabetes with insulin cells

A cure for type I diabetes has been brought closer why scientists who halted the conditions for six months using insulin producing cells

Researchers from American hospitals and institutions including Harvard University transplanted cells into mice the researchers were able to show they could prevent the cells being rendered useless by the body's immune system which was effectively "switched off" the findings potentially provide signals towards finding a cure for type I diabetes, which affects four hundred thousand people in Britain. Scientists are working to replicate the results in patients with the condition.

Scientists led by Doug Melton a professor at Harvard, discovered in late two thousand fourteen how to make huge quantities of insulin-producing cells. The islet cells used for the latest research were generated from human stem cells developed by Professor Melton

After implantation in the mice, the sales began to produce insulin in response to blood glucose levels, which remained within a healthy range for the length of the study. The findings were published in the journals Nature Medicine and in Nature Biotechnology.

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